Principally composed of collagen, bovine pericardium provides strength and extensibility. 

Pericardium is a tough, double-layered, collagenous membrane which covers the heart in all species. The space between the two membrane layers is filled with a fluid which protects the heart from external shock. The tissue is suitable for fabrication of heart valve leaflets and other cardiac device biomaterial applications such as vascular patching and repair. It is also used widely for surgical buttressing such as in pelvic floor reconstruction and bariatric stomach reduction.

Specialty Example Products
Cardiovascular

Heart valves
Vascular closure

General & Gastroenterology surgery Staple line reinforcement
Hernia reinforcement
Women's health Pelvic floor reconstruction

Heart Valves

Neonatal bovine pericardium is a good candidate tissue for use as leaflets in percutaneous bioprosthetic heart valves delivered using a trans-catheter method because it is thinner and more elastic than the adult form. Collagen Solutions has been granted a patent for the preparation and use of neonatal pericardium for several applications. 2014 New Research shows Neonatal Pericardia have Properties Useful for Heart Valve Leaflets

Hernia Repair

Repairing complex hernias in patients with severe obesity, diabetes, and exposed synthetic mesh can pose challenges for surgeons. Compromised circulation makes people vulnerable to postoperative infection and limits a full recovery without subsequent hernias. Selecting a biological graft that revascularizes quickly increases the chance of successful recovery. Bovine pericardium has a proven record of decreasing the risk of postoperative infection and assist in preventing hernia recurrence.

Pelvic Floor Reconstruction

Pelvic organ prolapse refers to loss of support of the anterior or posterior vaginal wall or the vaginal apex leading to protrusion into or out the vaginal canal of the bladder, rectum, small bowel, and uterus. Surgeons have recently begun to explore the use of bovine pericardium to replace weak tissues that permit prolapse.

Staple Line Reinforcement

Surgeons performing bariatric stomach reductions staple a portion of the stomach shut. The staple line is a weak point and can bleed or leak, so they use bovine pericardium as a reinforcing material to strengthen the staple line prior to closure.

Vascular Patches

Bovine pericardial patches have several advantages compared to prosthetic patches, including superior biocompatability, easy handling, less suture line bleeding and possibly reduced rates of infection. These advantages of bovine pericardium have led to its common use during carotid endarterectomy.